Our,Sina Pazhouhan Company R&D

Active Substances Extraction

The extraction process in Sina Pazhouhan Company is carried out industrially and with the highest efficiency. The extraction method is first well evaluated by the research and development team of this company; Then the evaluation tests are done on a laboratory scale and if the desired result is achieved, it enters the industrial production stage.
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First step

Active Substances Encapsulation

Encapsulation is a technique in which the effective substance in Nano or Micro dimensions is placed inside a polymer shell and its connection with the space outside the shell is cut off. This method is defined as a protective method for sensitive active ingredients. Encapsulation of plant and natural products can increase process capacity, improve storage conditions and resistance of materials, and reduce maintenance and production costs. Also, it is an effective way to protect materials against environmental conditions and improve the quality of the final product.
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Second step

Among several encapsulation methods, spray drying is the most effective and common method in this field. Sina Pazhouhan Company is one of the effective pioneers in the field of producing encapsulated powder extracts by having a spray dryer and other up-to-date and sufficient equipment in the production department and also due to the use of research methods obtained in its research and development department.

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Clinical studies

Over the years, Sina Pazhouhan Company has conducted several research projects in the form of human clinical designs. In addition, the company has been involved in a wide range of other research, particularly in the fields of phytochemistry and laboratory studies. In this regard, the research and development team of Sina Pazhouhan Company works with researchers from all over Iran, including prominent scientists from universities and research organizations (Tehran University of Medical Sciences, Shiraz University of Medical Sciences, Semnan University of Medical Sciences...
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, Shiraz University of Medical Sciences, Semnan University of Medical Sciences, and Yazd University of Medical Sciences) and also with research teams in prominent international universities (universities of America, Italy, United Arab Emirates and Egypt).

With the support of clinical trials, Sina Pazhouhan Company makes a significant in the place of herbal and natural materials in the future of medicine. This company is known for carrying out extensive projects and its technical knowledge, especially in the field of medicinal plants such as saffron, and is often considered by research groups for cooperation in research projects on herbal treatments. Sina Pazhouhan Company evaluates each of these requests carefully and applies strict criteria to evaluate them. Clinical trials must comply with the company’s criteria, including high quality, innovative and comprehensive herbal and natural solutions, and must be conducted in an accredited research institution.

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important clinical studies

Some important clinical studies conducted in the company in the field of clinical studies

Investigating the therapeutic effects of saffron in controlling dry eye disorders

Investigating the effects of saffron in the control of intestinal inflammatory diseases

Articles related to clinical studies

Download clinical studies articles

Protective Effect of Saffron in Mouse Colitis Models Through Immune (2021)

Protective Effect of Saffron in Mouse Colitis Models Through Immune (2021)

Download Article

Saffron and Its Major Ingredients’ Effect on Colon Cancer Cells (2021)

Saffron and Its Major Ingredients’ Effect on Colon Cancer Cells (2021)

Download Article

Saffron as an Adjuvant Therapy in Ulcerative Colitis Patients (2022)

Saffron as an Adjuvant Therapy in Ulcerative Colitis Patients (2022)

Download Article

Saffron Crudes and Compounds Restrict MACC1-Dependent Cell Proliferation and Migration of Colorectal Cancer Cells (2020)

Saffron Crudes and Compounds Restrict MACC1-Dependent Cell Proliferation and Migration of Colorectal Cancer Cells (2020)

Download Article

Saffron Pre-Treatment Promotes Reduction in Tissue Inflammatory Profiles and Alters Microbiome Composition in Experimental Colitis Mice (2021)

Saffron Pre-Treatment Promotes Reduction in Tissue Inflammatory Profiles and Alters Microbiome Composition in Experimental Colitis Mice (2021)

Download Article

Saffron, A Promising Adjuvant Therapy in Ulcerative Colitis - A Trial Evaluating Clinical and Laboratory Outcomes (2023)

Saffron, A Promising Adjuvant Therapy in Ulcerative Colitis – A Trial Evaluating Clinical and Laboratory Outcomes (2023)

Download Article

Saffron, Its Active Components, and Their Association with DNA and Histone Modification A Narrative Review of Current Knowledge (2022)

Saffron, Its Active Components, and Their Association with DNA and Histone Modification A Narrative Review of Current Knowledge (2022)

Download Article

Saffron, The Golden Spice with Therapeutic Properties on Digestive Diseases (2019)

Saffron, The Golden Spice with Therapeutic Properties on Digestive Diseases (2019)

Download Article

Active Substances Extraction

The extraction process in Sina Pazhouhan Company is carried out industrially and with the highest efficiency. The extraction method is first well evaluated by the research and development team of this company; Then the evaluation tests are done on a laboratory scale and if the desired result is achieved, it enters the industrial production stage.
Direction Arrows
First step

Active Substances Encapsulation

Encapsulation is a technique in which the effective substance in Nano or Micro dimensions is placed inside a polymer shell and its connection with the space outside the shell is cut off. This method is defined as a protective method for sensitive active ingredients. Encapsulation of plant and natural products can increase process capacity, improve storage conditions and resistance of materials, and reduce maintenance and production costs. Also, it is an effective way to protect materials against environmental conditions and improve the quality of the final product
Direction Arrows
Second step

Among several encapsulation methods, spray drying is the most effective and common method in this field. Sina Pazhouhan Company is one of the effective pioneers in the field of producing encapsulated powder extracts by having a spray dryer and other up-to-date and sufficient equipment in the production department and also due to the use of research methods obtained in its research and development department.

Read more Close

Clinical studies

Over the years, Sina Pazhouhan Company has conducted several research projects in the form of human clinical designs. In addition, the company has been involved in a wide range of other research, particularly in the fields of phytochemistry and laboratory studies. In this regard, the research and development team of Sina Pazhouhan Company works with researchers from all over Iran, including prominent scientists from universities and research organizations (Tehran University of Medical Sciences
Direction Arrows
Third step

Shiraz University of Medical Sciences, Semnan University of Medical Sciences, and Yazd University of Medical Sciences) and also with research teams in prominent international universities (universities of America, Italy, United Arab Emirates and Egypt).

With the support of clinical trials, Sina Pazhouhan Company makes a significant in the place of herbal and natural materials in the future of medicine. This company is known for carrying out extensive projects and its technical knowledge, especially in the field of medicinal plants such as saffron, and is often considered by research groups for cooperation in research projects on herbal treatments. Sina Pazhouhan Company evaluates each of these requests carefully and applies strict criteria to evaluate them. Clinical trials must comply with the company’s criteria, including high quality, innovative and comprehensive herbal and natural

Read more Close
important clinical studies

Some important clinical studies conducted in the company in the field of clinical studies

the therapeutic effects of saffron in controlling dry eye disorders

Investigating the effects of saffron in the control of intestinal inflammatory diseases

Articles related to clinical studies

Download clinical studies articles

Protective Effect of Saffron in Mouse Colitis Models Through Immune (2021)

Protective Effect of Saffron in Mouse Colitis Models Through Immune (2021)

Download Article

Saffron and Its Major Ingredients’ Effect on Colon Cancer Cells (2021)

Saffron and Its Major Ingredients’ Effect on Colon Cancer Cells (2021)

Download Article

Saffron as an Adjuvant Therapy in Ulcerative Colitis Patients (2022)

Saffron as an Adjuvant Therapy in Ulcerative Colitis Patients (2022)

Download Article

Saffron Crudes and Compounds Restrict MACC1-Dependent Cell Proliferation and Migration of Colorectal Cancer Cells (2020)

Saffron Crudes and Compounds Restrict MACC1-Dependent Cell Proliferation and Migration of Colorectal Cancer Cells (2020)

Download Article

Saffron Pre-Treatment Promotes Reduction in Tissue Inflammatory Profiles and Alters Microbiome Composition in Experimental Colitis Mice (2021)

Saffron Pre-Treatment Promotes Reduction in Tissue Inflammatory Profiles and Alters Microbiome Composition in Experimental Colitis Mice (2021)

Download Article

Saffron, A Promising Adjuvant Therapy in Ulcerative Colitis - A Trial Evaluating Clinical and Laboratory Outcomes (2023)

Saffron, A Promising Adjuvant Therapy in Ulcerative Colitis – A Trial Evaluating Clinical and Laboratory Outcomes (2023)

Download Article

Saffron, Its Active Components, and Their Association with DNA and Histone Modification A Narrative Review of Current Knowledge (2022)

Saffron, Its Active Components, and Their Association with DNA and Histone Modification A Narrative Review of Current Knowledge (2022)

Download Article

Saffron, The Golden Spice with Therapeutic Properties on Digestive Diseases (2019)

Saffron, The Golden Spice with Therapeutic Properties on Digestive Diseases (2019)

Download Article